Xenopus laevis

African clawed frog

Also known as: Bufo laevis

Indigenous / local names

Gewone platanna (af) Wikidata
Gewone Platanna (afr) GBIF ↗
Plathander (afr) GBIF ↗
Lentsweta le tlwaelehileng (sot) GBIF ↗
Segwagwa sa metsing se tlwaelegileng (tsn) GBIF ↗

Taxonomic classification

cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus; Xenopus laevis

View at source ↗

Genome browser

The assembly file for Xenopus laevis hasn't finished reaching the Hub yet — check back shortly.

Sequence records

genome (fasta)

mirrored

Origin: hub

15 downloads

First synced: 8/21/2026 · Last updated: 8/21/2026

Source: NCBI GCF_017654675.1 · View at source ↗

Download annotation (GFF3) · Download CDS (FASTA) · Download proteins (FASTA)

Collection: · Sex: female

Sequencing: PacBio RSII · Canu v. 1.6-132-gf9284f8 · 28.5x coverage

Released: 2021-04-12 · Submitted by: International Xenopus Sequencing Consortium

publiccc0AFDSI-SEQ-1

GoaT: Chromosome assembly · 2.74 Gb · scaffold N50 155,250,555 · 18 chromosomes · View at source ↗

Publicly accessible — no request needed.

Proteins (21)

sprtn — 565 aa

rad50.S — 1311 aa

neil3 — 616 aa

lsm14a-a — 471 aa

clasp1b — 1456 aa

nemp1b — 434 aa

xiap — 488 aa

ube2d4 — 147 aa

htra1 — 459 aa

yap1-a — 459 aa

transcriptome (fasta)

mirrored

Origin: hub

11 downloads

First synced: 8/21/2026 · Last updated: 8/21/2026

Source: ENA AB023815 · View at source ↗

Download CDS (FASTA) · Download proteins (FASTA)

Released: 1999-07-09

publiccc0AFDSI-SEQ-45

Publicly accessible — no request needed.

No AlphaFold DB proteome found for this species.

Proteomics (external sources)

PaxDb — real per-protein abundance

LOC100101274 (8355.Q5U4L0) — abundance 12707AFDSI-PROTEOMICS-1

gapdh (8355.Q8AY70) — abundance 11048AFDSI-PROTEOMICS-2

ppia (8355.Q8AVP8) — abundance 10964AFDSI-PROTEOMICS-3

Gapdh.S (8355.Q7ZY52) — abundance 10324AFDSI-PROTEOMICS-4

Vbis02 (8355.A0A1L8EXB4) — abundance 9950AFDSI-PROTEOMICS-5

Serpina6.L (8355.A0A1L8F9K5) — abundance 8404AFDSI-PROTEOMICS-6

A0A1L8HT50 (8355.A0A1L8HT50) — abundance 8215AFDSI-PROTEOMICS-7

eno1 (8355.A0A1L8FLY7) — abundance 7884AFDSI-PROTEOMICS-8

tpi1-2 (8355.A0A1L8FIG2) — abundance 7825AFDSI-PROTEOMICS-9

A0A1L8EJR5 (8355.A0A1L8EJR5) — abundance 7476AFDSI-PROTEOMICS-10

PRIDE — project-level reference (metadata only; no per-protein identifications are available via PRIDE's public API)

A dual-anchoring mechanism for the hemimethylated CG-guided histone ubiquitylation (PXD079072) ↗AFDSI-PROJREF-60

Analysis of Zyxin's interactome and phosphosites in early Xenopus laevis development by Data-Dependent Acquisition proteomics (PXD071283) ↗AFDSI-PROJREF-61

Analysis of Zyxin's interactome and phosphosites in early Xenopus laevis development by Data-Independent Acquisition proteomics (PXD071213) ↗AFDSI-PROJREF-62

Proteomic of nuptial pads of Xenopus laevis (African clawed frog) (PXD071004) ↗AFDSI-PROJREF-63

Greatwall depletion from Xenopus oocytes reveals a key role of the cyclin B/CDK1-PP2A-B55 balance in the coordination of meiotic events. (PXD068132) ↗AFDSI-PROJREF-64

DNA polymerase kappa is the primary translesion synthesis polymerase for aldehyde ICLs (PXD066315) ↗AFDSI-PROJREF-65

Deciphering the dynamic proteome of multiciliated cells (PXD064476) ↗AFDSI-PROJREF-66

Subcellular Mass Spectrometry Reveals Proteome Remodeling in an Asymmetrically Dividing (Frog) Embryonic Stem Cell (PXD063566) ↗AFDSI-PROJREF-67

Histone variant H2A.Z enhances histone and nucleosome dynamics (PXD062956) ↗AFDSI-PROJREF-68

Live Electrophoresis-Correlative AI Democratizes Single-cell Mass Spectrometry Proteomics (PXD062702) ↗AFDSI-PROJREF-69

Chemical Profiles (external sources)

ChEMBL rows are compounds active against a protein target from this organism — not confirmed as compounds the species itself produces, unlike ANPDB's.

ChEMBL: CHEMBL228043 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 10300.0 nMAFDSI-METABOLOMICS-67

ChEMBL: CHEMBL27130 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; EC50 nMAFDSI-METABOLOMICS-45

ChEMBL: CHEMBL29024 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; EC50 nMAFDSI-METABOLOMICS-46

ChEMBL: CHEMBL28472 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; EC50 nMAFDSI-METABOLOMICS-47

ChEMBL: CHEMBL15013 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; ActivityAFDSI-METABOLOMICS-48

ChEMBL: CHEMBL39187 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; ActivityAFDSI-METABOLOMICS-49

ChEMBL: CHEMBL43190 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; ActivityAFDSI-METABOLOMICS-50

ChEMBL: CHEMBL40140 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; ActivityAFDSI-METABOLOMICS-51

ChEMBL: CHEMBL39903 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; ActivityAFDSI-METABOLOMICS-52

ChEMBL: CHEMBL42867 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; ActivityAFDSI-METABOLOMICS-53

ChEMBL: MELATONIN (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; ActivityAFDSI-METABOLOMICS-54

ChEMBL: CHEMBL39998 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; ActivityAFDSI-METABOLOMICS-55

ChEMBL: CHEMBL37514 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; ActivityAFDSI-METABOLOMICS-56

ChEMBL: CHEMBL53824 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; EC50 0.7 nMAFDSI-METABOLOMICS-57

ChEMBL: CHEMBL345090 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; EC50 132.0 nMAFDSI-METABOLOMICS-58

ChEMBL: CHEMBL143547 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; EC50 470.0 nMAFDSI-METABOLOMICS-59

ChEMBL: CHEMBL143125 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; EC50 789.0 nMAFDSI-METABOLOMICS-60

ChEMBL: CHEMBL143074 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; EC50 128.0 nMAFDSI-METABOLOMICS-61

ChEMBL: CHEMBL428169 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 1000.0 nMAFDSI-METABOLOMICS-62

ChEMBL: CHEMBL219755 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 500.0 nMAFDSI-METABOLOMICS-63

ChEMBL: CHEMBL424754 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 300.0 nMAFDSI-METABOLOMICS-64

ChEMBL: CHEMBL436918 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 2000.0 nMAFDSI-METABOLOMICS-65

ChEMBL: CHEMBL372401 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50AFDSI-METABOLOMICS-66

Metabolic Profiles (external sources)

MetaboLights: Diversity in DNA: Identification of methylated deoxyadenosines in higher eukaryotes (View at source ↗)AFDSI-METABPROF-9

KEGG: KEGG genome-based metabolic profile (xla) (View at source ↗) — Genome-based pathway inference (KEGG) — reflects which metabolic pathways this species' annotated genes place it in, not experimentally measured metabolite presenceAFDSI-METABPROF-19

Protein Structures

nemp1a — v2

pLDDT confidence: 0.0

Native

publiccc_byAFDSI-STRUCT-6058-V2

protein 109 — v2

pLDDT confidence: unknown

Auto-synced from PDBe 8vhi · View at source ↗

publiccc_byAFDSI-STRUCT-476-V2

has2 — v2

pLDDT confidence: 90.4

Auto-synced from AlphaFold DB AF-O57427-F1 · View at source ↗

publiccc_byAFDSI-STRUCT-12525-V2

lsm14a-a — v1

pLDDT confidence: 58.6

Auto-synced from AlphaFold DB AF-A0A8M2-F1 · View at source ↗

publiccc_byAFDSI-STRUCT-453-V1

clasp1b — v1

pLDDT confidence: 70.6

Auto-synced from AlphaFold DB AF-A1A5K2-F1 · View at source ↗

publiccc_byAFDSI-STRUCT-454-V1

Field & Specimen Imaging

camera_trap at South Africa · Source: GBIF 5938098882 (View at source ↗)AFDSI-IMG-106

camera_trap at South Africa · Source: GBIF 5938656457 (View at source ↗)AFDSI-IMG-107

camera_trap at South Africa · Source: GBIF 6129850357 (View at source ↗)AFDSI-IMG-108

camera_trap at South Africa · Source: GBIF 6129878566 (View at source ↗)AFDSI-IMG-109

camera_trap at South Africa · Source: GBIF 6129911136 (View at source ↗)AFDSI-IMG-110

camera_trap at South Africa · Source: GBIF 6129939379 (View at source ↗)AFDSI-IMG-237

camera_trap at South Africa · Source: GBIF 6130017680 (View at source ↗)AFDSI-IMG-240

camera_trap at South Africa · Source: GBIF 6130041961 (View at source ↗)AFDSI-IMG-241

camera_trap at South Africa · Source: GBIF 6130100033 (View at source ↗)AFDSI-IMG-242

camera_trap at South Africa · Source: GBIF 6130207688 (View at source ↗)AFDSI-IMG-244

Cellular & Molecular Imaging (external sources)

BioImage Archive: Modular, portable, high-end microscopy inside and outside the lab (View on source archive ↗)AFDSI-CELL-20

BioImage Archive: The increase of Cyclin A/cdk activity and of FAM122A-dependent inhibition of PP2A-B55 are key events to trigger mitosis (View on source archive ↗)AFDSI-CELL-21

BioImage Archive: The Benchtop mesoSPIM: a next-generation open-source light-sheet microscope for large cleared samples (View on source archive ↗)AFDSI-CELL-22

BioImage Archive: (View on source archive ↗)AFDSI-CELL-23

BioImage Archive: Phosphorylation of Xenopus M18BP1 governs centromeric localization and CENP-A nucleosome assembly (EMBO Reports) (View on source archive ↗)AFDSI-CELL-15

BioImage Archive: Prickle and Ror modulate Dishevelled-Vangl interaction to regulate non-canonical Wnt signaling during convergent extension in Xenopus (View on source archive ↗)AFDSI-CELL-16

BioImage Archive: Prickle and Ror modulate Dishevelled-Vangl interaction to regulate non-canonical Wnt signaling during convergent extension in Xenopus (View on source archive ↗)AFDSI-CELL-17

BioImage Archive: Palmitoylated Importin Alpha Regulates Mitotic Spindle Orientation Through Interaction with NuMA (View on source archive ↗)AFDSI-CELL-18

BioImage Archive: Single-cell morphodynamics predict cell fate decisions during mucociliary epithelial differentiation (View on source archive ↗)AFDSI-CELL-19

Geographic range (Africa)

4,903 real GBIF-recorded occurrences across Africa — see this species on GBIF ↗.

This reflects real occurrence records submitted to GBIF, not a comprehensive range map — sampling effort varies significantly by country and region, so an absence here doesn't mean the species isn't present.