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The pathogen/wildlife-reservoir-host dimension of the One Health nexus — a pilot linking African-endemic pathogens to their documented wildlife reservoir hosts. Genomes, proteins, and structures for both sides are catalogued the same way as every other species on this platform; this page records the relationship between them specifically. Every association is curated against a real, citable publication, by a curator or a Continental Admin, reviewed before publication, and marked honestly as confirmed or still-suspected science — reservoir attribution is genuinely contested for several of these pathogens, and this page never presents a suspected link as settled fact. Evidence from a preprint, not yet peer-reviewed, is recorded at most as suspected.
Researchers can help curate these pairs and are credited for it.
Status in Africa is set by a curator; species not yet assessed are marked so. Each species page also shows where GBIF and this Hub's genomes record it.
Download all 20 as CSV ↓ (with each one's paper, statuses and curators) · Our curators
Pathogen: Endemic to Africa Host: Introduced
Utilized a library of uniquely barcoded B. abortus strains to quantify population structure during colonization of cattle through a natural route of infection.
Evidence: Fiebig A, Vrentas CE, Le T, Huebner M, Boggiatto PM, Olsen SC, Crosson S. Quantification of Brucella abortus population structure in a natural host. Proc Natl Acad Sci U S A (2021). https://doi.org/10.1073/pnas.2023500118. PMID: 33688053. AFDSI-ASSOC-59
Curated by Ms. Sarah C. Ihenko (University of Cambridge, United Kingdom) · ORCID 0009-0009-8896-7809 . Reviewed by the African DSI DataBank.
Pathogen: Cosmopolitan Host: Introduced
Staphylococcus spp. was isolated in 46% of cases (119/256), with Staphylococcus pseudintermedius being the most prevalent species
Evidence: Nocera FP, Romano A, Arslan S, Schena R, Pizzano F, Cappiello S, Palma CD, Lamagna B, Pompameo M, De Martino L. Occurrence and Antimicrobial Resistance Profiles of Staphylococcus spp. Strains Isolated From Healthy Stray Dogs. Vet Med Sci (2025). https://doi.org/10.1002/vms3.70599. PMID: 40944940. AFDSI-ASSOC-20
Curated by Ms. Sarah C. Ihenko (University of Cambridge, United Kingdom) · ORCID 0009-0009-8896-7809 . Reviewed by the African DSI DataBank.
Pathogen: Cosmopolitan Host: Cosmopolitan
Sequenced 90 S. aureus isolates: 46 isolates from invasive disease in humans, 13 human carriage isolates, and 31 monkey carriage isolates.
Evidence: Senghore M, Bayliss SC, Kwambana-Adams BA, Foster-Nyarko E, Manneh J, Dione M, Badji H, Ebruke C, Doughty EL, Thorpe HA, Jasinska AJ, Schmitt CA, Cramer JD, Turner TR, Weinstock G, Freimer NB, Pallen MJ, Feil EJ, Antonio M. Transmission of Staphylococcus aureus from Humans to Green Monkeys in The Gambia as Revealed by Whole-Genome Sequencing. Appl Environ Microbiol (2016). https://doi.org/10.1128/AEM.01496-16. PMID: 27474712. AFDSI-ASSOC-19
Curated by Ms. Sarah C. Ihenko (University of Cambridge, United Kingdom) · ORCID 0009-0009-8896-7809 . Reviewed by the African DSI DataBank.
Pathogen: Cosmopolitan Host: Native to Africa
Staphylococci (including Staphylococcus aureus) were cultured from swabs from 44 bats (skin, oropharynx, mouth ejecta, skin lesions) and from their enclosure.
Evidence: Fountain K, Roberts L, Young V, Barbon A, Frosini SM, Lloyd DH, Loeffler A. DIVERSITY OF STAPHYLOCOCCAL SPECIES CULTURED FROM CAPTIVE LIVINGSTONE'S FRUIT BATS (PTEROPUS LIVINGSTONII) AND THEIR ENVIRONMENT. J Zoo Wildl Med (2019). https://doi.org/10.1638/2018-0121. PMID: 31120689. AFDSI-ASSOC-17
Curated by Ms. Sarah C. Ihenko (University of Cambridge, United Kingdom) · ORCID 0009-0009-8896-7809 . Reviewed by the African DSI DataBank.
Pathogen: Cosmopolitan Host: Domesticated
Isolated Staphylococcus aureus from a nasal swab of a dromedary camel (Camelus dromedarius) and sequenced its genome.
Evidence: Zubair S, Fischer A, Liljander A, Meens J, Hegerman J, Gourlé H, Bishop RP, Roebbelen I, Younan M, Mustafa MI, Mushtaq M, Bongcam-Rudloff E, Jores J. Complete genome sequence of Staphylococcus aureus, strain ILRI_Eymole1/1, isolated from a Kenyan dromedary camel. Stand Genomic Sci (2015). https://doi.org/10.1186/s40793-015-0098-6. PMID: 26594310. AFDSI-ASSOC-15
Curated by Ms. Sarah C. Ihenko (University of Cambridge, United Kingdom) · ORCID 0009-0009-8896-7809 . Reviewed by the African DSI DataBank.
Pathogen: Cosmopolitan Host: Introduced
Klebsiella pneumoniae strain (KP411) recovered from the stool samples of poultry (Gallus gallus)
Evidence: Valiatti TB, Cayô R, Santos FF, Bessa-Neto FO, Brandão Silva RG, Veiga R, de Nazaré Miranda Bahia M, Guerra LMGD, Pignatari ACC, de Oliveira Souza C, Brasiliense DM, Gales AC, Guarani Network. Genomic Analysis of Klebsiella pneumoniae ST258 Strain Coproducing KPC-2 and CTX-M-14 Isolated from Poultry in the Brazilian Amazon Region. Antibiotics (Basel) (2022). https://doi.org/10.3390/antibiotics11121835. PMID: 36551493. AFDSI-ASSOC-18
Curated by Ms. Sarah C. Ihenko (University of Cambridge, United Kingdom) · ORCID 0009-0009-8896-7809 . Reviewed by the African DSI DataBank.
Pathogen: Endemic in Africa Host: Domesticated
Seven Streptococcus agalactiae strains isolated from Camelus dromedarius
Evidence: Rothen J, Schindler T, Pothier JF, Younan M, Certa U, Daubenberger C, Pflüger V, Jores J. Draft Genome Sequences of Seven Streptococcus agalactiae Strains Isolated from Camelus dromedarius at the Horn of Africa. Genome Announc (2017). https://doi.org/10.1128/genomeA.00525-17. PMID: 28705964. AFDSI-ASSOC-14
Curated by Ms. Sarah C. Ihenko (University of Cambridge, United Kingdom) · ORCID 0009-0009-8896-7809 . Reviewed by the African DSI DataBank.
Pathogen: Cosmopolitan Host: Endemic to Africa
Landmark study establishing Agama agama as a natural intestinal host reservoir for Salmonella enterica
Evidence: COLLARD P, MONTEFIORE D. The agama lizard as reservoir of Salmonellae in Nigeria. Nature (1957). https://doi.org/10.1038/179164b0. PMID: 13400133. AFDSI-ASSOC-13
Curated by Ms. Sarah C. Ihenko (University of Cambridge, United Kingdom) · ORCID 0009-0009-8896-7809 . Reviewed by the African DSI DataBank.
Pathogen: Endemic in Africa Host: Native to Africa
Obtained 68 caecal isolates of Escherichia coli from 10 chickens and 9 guinea fowl (Numididae)
Evidence: Foster-Nyarko E, Alikhan NF, Ravi A, Thomson NM, Jarju S, Kwambana-Adams BA, Secka A, O'Grady J, Antonio M, Pallen MJ. Genomic diversity of Escherichia coli isolates from backyard chickens and guinea fowl in the Gambia. Microb Genom (2021). https://doi.org/10.1099/mgen.0.000484. PMID: 33253086. AFDSI-ASSOC-16
Curated by Ms. Sarah C. Ihenko (University of Cambridge, United Kingdom) · ORCID 0009-0009-8896-7809 . Reviewed by the African DSI DataBank.
Pathogen: Cosmopolitan Host: Native to Africa
Recovered Salmonella enterica from ileocecal lymph nodes (26.0%), carcass surface swabs (16.0%), and pork meat (14.0%) of 100 slaughtered pigs
Evidence: Gomes-Neves E, Antunes P, Tavares A, Themudo P, Cardoso MF, Gärtner F, Costa JM, Peixe L. Salmonella cross-contamination in swine abattoirs in Portugal: Carcasses, meat and meat handlers. Int J Food Microbiol (2012). https://doi.org/10.1016/j.ijfoodmicro.2012.04.015. PMID: 22607810. AFDSI-ASSOC-12
Curated by Ms. Sarah C. Ihenko (University of Cambridge, United Kingdom) · ORCID 0009-0009-8896-7809 . Reviewed by the African DSI DataBank.