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Drosophila melanogaster

fruit fly

taxon 7227

Also known as: Sophophora melanogaster

Indigenous / local names

No local or indigenous names recorded yet.

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Sequence records

genome (fasta)

mirrored

Origin: hub

1 download

First synced: 8/26/2026 · Last updated: 8/26/2026

Source: NCBI GCA_042606465.1 · View at source ↗

Collection: · Sex: male

Sequencing: PacBio · HiFiasm v. 0.16.1 · 163x coverage

publiccc0AFDSI-SEQ-242

GoaT: Chromosome assembly · 0.14 Gb · scaffold N50 25,286,936 · BUSCO 98.7% complete · 7 chromosomes · View at source ↗

Publicly accessible — no request needed.

transcriptome (fasta)

mirrored

Origin: hub

0 downloads

First synced: 8/26/2026 · Last updated: 8/26/2026

Source: NCBI QT396907.1 · View at source ↗

publiccc0AFDSI-SEQ-597

Publicly accessible — no request needed.

AlphaFold DB proteome: UP000107534

Proteomics (external sources)

PaxDb — real per-protein abundance

CG7214 (7227.FBpp0079122) — abundance 10090AFDSI-PROTEOMICS-151

Yp3 (7227.FBpp0311924) — abundance 10077AFDSI-PROTEOMICS-152

CG7203 (7227.FBpp0312122) — abundance 9069AFDSI-PROTEOMICS-153

Yp1 (7227.FBpp0312020) — abundance 8855AFDSI-PROTEOMICS-154

Acp1 (7227.FBpp0079123) — abundance 8690AFDSI-PROTEOMICS-155

Yp2 (7227.FBpp0308710) — abundance 8475AFDSI-PROTEOMICS-156

Adh (7227.FBpp0100048) — abundance 7829AFDSI-PROTEOMICS-157

awd (7227.FBpp0311978) — abundance 7753AFDSI-PROTEOMICS-158

ATPsynbeta (7227.FBpp0305828) — abundance 7359AFDSI-PROTEOMICS-159

RpL35 (7227.FBpp0070767) — abundance 6920AFDSI-PROTEOMICS-160

PRIDE — project-level reference (metadata only; no per-protein identifications are available via PRIDE's public API)

Polo/PLK1 phosphorylation relieves Centrosomin (Cnn) autoinhibition to drive centrosome scaffold assembly (PXD080319) ↗AFDSI-PROJREF-147

Multiple intron motifs have redundant functions in trans-splicing of the mod(mdg4) locus (PXD079014) ↗AFDSI-PROJREF-148

RpS12-mediated induction of the Xrp1short isoform links ribosomal protein mutations to cell competition (PXD076715) ↗AFDSI-PROJREF-149

Microbiota-induced fatty acid synthesis facilitates intestinal infection and immune-mediated damage in Drosophila (PXD076700) ↗AFDSI-PROJREF-150

Autophagy-driven Presynaptic Reorganization as a Molecular Signature of Brain Resilience (PXD076163) ↗AFDSI-PROJREF-151

Identification of dArc binding partners from mouse C2C12 cells (PXD075863) ↗AFDSI-PROJREF-152

Adipose Dicer-1 modulates systemic insulin signaling and longevity via a miR-8–Aop–Dilp6 axis (PXD075513) ↗AFDSI-PROJREF-153

putzig safeguards genome integrity by contributing to the Piwi-mediated repression of transposon activity in the female germline of Drosophila in a two-tiered fashion (PXD075330) ↗AFDSI-PROJREF-154

Cryo-EM structure, enzymatic activity and genome targeting of canonical PRC1 (PXD074618) ↗AFDSI-PROJREF-155

HR3/RORα-mediated cholesterol sensing regulates TOR signaling (PXD074014) ↗AFDSI-PROJREF-156

Chemical Profiles (external sources)

ChEMBL rows are compounds active against a protein target from this organism — not confirmed as compounds the species itself produces, unlike ANPDB's.

ChEMBL: CHEMBL400618 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 163000.0 nMAFDSI-METABOLOMICS-283

ChEMBL: CHEMBL103283 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 65000.0 nMAFDSI-METABOLOMICS-284

ChEMBL: CHEMBL605255 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 31600.0 nMAFDSI-METABOLOMICS-285

ChEMBL: CHEMBL238635 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 178000.0 nMAFDSI-METABOLOMICS-286

ChEMBL: CHEMBL400411 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 1000000.0 nMAFDSI-METABOLOMICS-287

ChEMBL: CHEMBL3143826 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 1000000.0 nMAFDSI-METABOLOMICS-288

ChEMBL: CHEMBL400410 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 1000000.0 nMAFDSI-METABOLOMICS-289

ChEMBL: CHEMBL392957 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 872000.0 nMAFDSI-METABOLOMICS-290

ChEMBL: CYTARABINE (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 5319000.0 nMAFDSI-METABOLOMICS-291

ChEMBL: CHEMBL392346 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 1000000.0 nMAFDSI-METABOLOMICS-292

ChEMBL: FOSTRIECIN (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 40000.0 nMAFDSI-METABOLOMICS-293

ChEMBL: CHEMBL89464 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 23000.0 nMAFDSI-METABOLOMICS-294

ChEMBL: CHEMBL88409 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 29000.0 nMAFDSI-METABOLOMICS-295

ChEMBL: CHEMBL91382 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 2200.0 nMAFDSI-METABOLOMICS-296

ChEMBL: CHEMBL92495 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 132000.0 nMAFDSI-METABOLOMICS-297

ChEMBL: CHEMBL606989 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 300000.0 nMAFDSI-METABOLOMICS-298

ChEMBL: ADOCIAQUINONE A (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC90 118000.0 nMAFDSI-METABOLOMICS-299

ChEMBL: CHEMBL138236 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC90 135000.0 nMAFDSI-METABOLOMICS-300

ChEMBL: ADOCIAQUINONE B (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC90 78000.0 nMAFDSI-METABOLOMICS-301

ChEMBL: CHEMBL138922 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC90 135000.0 nMAFDSI-METABOLOMICS-302

ChEMBL: CHEMBL155621 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 147.91 nMAFDSI-METABOLOMICS-303

ChEMBL: CHEMBL155396 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 1412.54 nMAFDSI-METABOLOMICS-304

ChEMBL: CHEMBL155514 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 0.537 nMAFDSI-METABOLOMICS-305

ChEMBL: 2-DECANONE (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 7079457.84 nMAFDSI-METABOLOMICS-306

ChEMBL: CHEMBL152843 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 6760.83 nMAFDSI-METABOLOMICS-307

ChEMBL: CHEMBL153177 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 346.74 nMAFDSI-METABOLOMICS-308

ChEMBL: CHEMBL150648 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 79432.82 nMAFDSI-METABOLOMICS-309

ChEMBL: CHEMBL421992 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 83.18 nMAFDSI-METABOLOMICS-310

ChEMBL: CHEMBL356917 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 398.11 nMAFDSI-METABOLOMICS-311

ChEMBL: CHEMBL152225 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 35481.34 nMAFDSI-METABOLOMICS-312

ChEMBL: CHEMBL443149 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; ActivityAFDSI-METABOLOMICS-313

ChEMBL: CHEMBL486188 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; ActivityAFDSI-METABOLOMICS-314

ChEMBL: destruxin A4 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; LC50 41.0 ppmAFDSI-METABOLOMICS-315

ChEMBL: homodestruxin B (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; ActivityAFDSI-METABOLOMICS-316

ChEMBL: DESTRUXIN A5 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; LC50 52.0 ppmAFDSI-METABOLOMICS-317

ChEMBL: CHEMBL573427 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; ActivityAFDSI-METABOLOMICS-318

ChEMBL: HYMENOIC ACID (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; ActivityAFDSI-METABOLOMICS-319

ChEMBL: CHEMBL3127729 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 200000.0 nMAFDSI-METABOLOMICS-320

ChEMBL: CHEMBL3127728 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 200000.0 nMAFDSI-METABOLOMICS-321

ChEMBL: CHEMBL3127730 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 200000.0 nMAFDSI-METABOLOMICS-322

ChEMBL: PECILOCIN (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 200000.0 nMAFDSI-METABOLOMICS-323

Metabolic Profiles (external sources)

MetaboLights: Rapid metabolic shifts occur during the transition between hunger and satiety in Drosophila melanogaster (View at source ↗)AFDSI-METABPROF-43

MetaboLights: Prediction of complex phenotypes using the Drosophila melanogaster metabolome (View at source ↗)AFDSI-METABPROF-44

MetaboLights: Exposure to environmental hazard pesticide rotenone triggers redox driven system-wide lipidome alterations and metabolic trade-offs linked to Parkinson’s disease (View at source ↗)AFDSI-METABPROF-42

MetaboLights: Chronic sleep loss sensitizes Drosophila melanogaster to nitrogen stress (View at source ↗)AFDSI-METABPROF-45

MetaboLights: Genotype to phenotype: Diet-by-mitochondrial DNA haplotype interactions drive metabolic flexibility and organismal fitness (View at source ↗)AFDSI-METABPROF-46

MetaboLights: Metabolic reaction network-based recursive metabolite annotation for untargeted metabolomics (Aging fruit fly negative mode) (View at source ↗)AFDSI-METABPROF-195

MetaboLights: Metabolic reaction network-based recursive metabolite annotation for untargeted metabolomics (Aging fruit fly positive mode) (View at source ↗)AFDSI-METABPROF-177

MetaboLights: Host autophagy mediates organ wasting and nutrient mobilization for tumor growth (View at source ↗)AFDSI-METABPROF-178

KEGG: KEGG genome-based metabolic profile (dme) (View at source ↗) — Genome-based pathway inference (KEGG) — reflects which metabolic pathways this species' annotated genes place it in, not experimentally measured metabolite presenceAFDSI-METABPROF-103

Cellular & Molecular Imaging (external sources)

IDR: Regulation of single-cell genome organization into TADs and chromatin nanodomains (View on source archive ↗)AFDSI-CELL-29

IDR: Dynamics of Drosophila endoderm specification (View on source archive ↗)AFDSI-CELL-30

IDR: Regulation of single-cell genome organization into TADs and chromatin nanodomains (View on source archive ↗)AFDSI-CELL-31

IDR: A timer gene network is spatially regulated by the terminal system in the Drosophila embryo (View on source archive ↗)AFDSI-CELL-28

BioImage Archive: Diffusible fraction of niche BMP ligand safeguards stem-cell differentiation (View on source archive ↗)AFDSI-CELL-313

BioImage Archive: Agrotoxin - Drosophila melanogaster screen (View on source archive ↗)AFDSI-CELL-314

BioImage Archive: (View on source archive ↗)AFDSI-CELL-315

BioImage Archive: (View on source archive ↗)AFDSI-CELL-316

BioImage Archive: Drosophila Alms1 proteins regulate centriolar cartwheel assembly by enabling Plk4-Ana2 amplification (View on source archive ↗)AFDSI-CELL-317

BioImage Archive: An integrated anatomical, functional and evolutionary view of the Drosophila olfactory system (View on source archive ↗)AFDSI-CELL-318

Geographic range (Africa)

151 real GBIF-recorded occurrences across Africa — see this species on GBIF ↗.

This reflects real occurrence records submitted to GBIF, not a comprehensive range map — sampling effort varies significantly by country and region, so an absence here doesn't mean the species isn't present.