Plasmodium falciparum
malaria parasite P. falciparum
taxon 5833Also known as: Plasmodium (Laverania) falciparum
Indigenous / local names
- Plasmodium falciparum (af) Wikidata ↗
Genome browser
Sequence records
genome (fasta)
mirroredOrigin: hub
2 downloads
First synced: 8/26/2026 · Last updated: 8/26/2026
Source: NCBI GCA_019802515.2 · View at source ↗
Sequencing: PacBio RSII; Illumina · MaSuRCA v. 4.1.0 · 111x coverage
publiccc0AFDSI-SEQ-177GoaT: Contig assembly · 0.02 Gb · scaffold N50 1,517,128 · View at source ↗
Publicly accessible — no request needed.
transcriptome (fasta)
mirroredOrigin: hub
0 downloads
First synced: 8/26/2026 · Last updated: 8/26/2026
Source: NCBI AB080994.1 · View at source ↗
publiccc0AFDSI-SEQ-651Publicly accessible — no request needed.
No AlphaFold DB proteome found for this species.
Proteomics (external sources)
PRIDE — project-level reference (metadata only; no per-protein identifications are available via PRIDE's public API)
Plasmodium falciparum PfMyoF with a Rab-like tail domain associates with perinuclear membranes and trafficking proteins (PXD077305) ↗AFDSI-PROJREF-259
The translatome of quiescent Plasmodium falciparum gametocytes reveals parasite pyridoxal 5’-phosphate (PLP) biosynthesis is essential for efficient mosquito stage development (PXD075878) ↗AFDSI-PROJREF-260
TurboID Proximity Profiling of FIKK10.2 (PF3D7_1039000) in Plasmodium falciparum–Infected Red Blood Cells During Febrile Heat Stress (PXD073890) ↗AFDSI-PROJREF-261
Phosphoproteomics of Plasmodium falciparum infected red blood cells under Heat Stress (PXD073843) ↗AFDSI-PROJREF-262
Functional characterisation of components in two Plasmodium falciparum Cullin-RING-Ligase complexes (PXD072749) ↗AFDSI-PROJREF-263
Validation of Solvent Proteome Profiling for Antimalarial Drug Target Deconvolution (PXD071156) ↗AFDSI-PROJREF-264
High-resolution spatial proteomics of Plasmodium falciparum schizonts using hyperLOPIT and TMT-based mass spectrometry (PXD070842) ↗AFDSI-PROJREF-265
Determination of highly accurate small molecule:protein affinity constants at amino acid resolution using Hydrogen Deuterium Exchange Mass Spectrometry (HDX-MS) (PXD070051) ↗AFDSI-PROJREF-266
Plasmofraction: Deciphering membrane protein complexes in Plasmodium falciparum gametocytes via integrative structural systems biology (PXD068680) ↗AFDSI-PROJREF-267
Deciphering Membrane Protein Complexes in Plasmodium falciparum Gametocytes via Cross-Linking Mass Spectrometry and Structural Modeling (PXD067699) ↗AFDSI-PROJREF-268
Chemical Profiles (external sources)
ChEMBL rows are compounds active against a protein target from this organism — not confirmed as compounds the species itself produces, unlike ANPDB's.
ChEMBL: CHLOROQUINE PHOSPHATE (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition %AFDSI-METABOLOMICS-458
ChEMBL: CHEMBL107943 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition %AFDSI-METABOLOMICS-459
ChEMBL: CHEMBL111647 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition %AFDSI-METABOLOMICS-460
ChEMBL: CHEMBL325991 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition %AFDSI-METABOLOMICS-461
ChEMBL: CHEMBL108309 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition %AFDSI-METABOLOMICS-462
ChEMBL: CHEMBL326696 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition %AFDSI-METABOLOMICS-463
ChEMBL: QUINDOLINE (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition %AFDSI-METABOLOMICS-464
ChEMBL: CHEMBL108626 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition %AFDSI-METABOLOMICS-465
ChEMBL: CHEMBL418838 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition %AFDSI-METABOLOMICS-466
ChEMBL: CRYPTOLEPTINE IODIDE (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition %AFDSI-METABOLOMICS-467
ChEMBL: CHEMBL111720 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Ki 822.0 nMAFDSI-METABOLOMICS-686
ChEMBL: CHEMBL162898 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Ki 469.0 nMAFDSI-METABOLOMICS-687
ChEMBL: CHEMBL163038 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Ki 2000.0 nMAFDSI-METABOLOMICS-688
ChEMBL: CHEMBL162454 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Ki 530.0 nMAFDSI-METABOLOMICS-689
ChEMBL: CHEMBL349737 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Ki 437.0 nMAFDSI-METABOLOMICS-690
ChEMBL: CHEMBL115660 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Ki 27.0 nMAFDSI-METABOLOMICS-691
ChEMBL: CHEMBL325240 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Ki 6.7 nMAFDSI-METABOLOMICS-692
ChEMBL: CHEMBL116267 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Ki 59.0 nMAFDSI-METABOLOMICS-693
ChEMBL: CHEMBL116282 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Ki 53.0 nMAFDSI-METABOLOMICS-694
ChEMBL: CHEMBL112212 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Ki 32.0 nMAFDSI-METABOLOMICS-695
ChEMBL: CHEMBL41319 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; k obs / 1AFDSI-METABOLOMICS-696
ChEMBL: CHEMBL39246 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; k obs / 1AFDSI-METABOLOMICS-697
ChEMBL: CHEMBL41203 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; k obs / 1AFDSI-METABOLOMICS-698
ChEMBL: CHEMBL38598 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; k obs / 1AFDSI-METABOLOMICS-699
ChEMBL: CHEMBL38029 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; k obs / 1AFDSI-METABOLOMICS-700
ChEMBL: CHEMBL40135 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; k obs / 1AFDSI-METABOLOMICS-701
ChEMBL: CHEMBL323465 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Ki 490.0 nMAFDSI-METABOLOMICS-702
ChEMBL: CHEMBL431861 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 65000.0 nMAFDSI-METABOLOMICS-703
ChEMBL: CHEMBL324234 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 100000.0 nMAFDSI-METABOLOMICS-704
ChEMBL: CHEMBL107770 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 40000.0 nMAFDSI-METABOLOMICS-705
Metabolic Profiles (external sources)
MetaboLights: A conserved metabolic signature associated with response to fast-acting antimalarial agents (View at source ↗)AFDSI-METABPROF-70
MetaboLights: Analysis of sex-specific lipid metabolism of Plasmodium falciparum points to the importance of sphingomyelin for gametocytogenesis (View at source ↗)AFDSI-METABPROF-71
MetaboLights: A female gametocyte-specific ABC transporter plays a role in lipid metabolism in the malaria parasite (View at source ↗)AFDSI-METABPROF-72
MetaboLights: MaHPIC Experiment HuB - Metabolomics analysis of human plasma from patients infected with Plasmodium falciparum and P.vivax for discovery of diagnostic markers of malaria (View at source ↗)AFDSI-METABPROF-73
MetaboLights: Mechanisms of PfDNMT2 inhibition and PfATP6-mediated resistance to the antimalarial candidate SC83288 in Plasmodium falciparum (View at source ↗)AFDSI-METABPROF-74
Cellular & Molecular Imaging (external sources)
BioImage Archive: Actomyosin forces and the energetics of red blood cell invasion by the malaria parasite Plasmodium falciparum (View on source archive ↗)AFDSI-CELL-592
BioImage Archive: tRNA lysidinylation is essential for the minimal translation system found in the apicoplast of Plasmodium falciparum (View on source archive ↗)AFDSI-CELL-593
BioImage Archive: Plasmodium falciparum impairs Ang-1 secretion by pericytes in a 3D brain microvessel model (View on source archive ↗)AFDSI-CELL-594
BioImage Archive: Machine Learning-based Phenotypic Imaging to Characterise the Targetable Biology of Plasmodium falciparum Male Gametocytes for Transmission-Blocking Antimalarials (View on source archive ↗)AFDSI-CELL-595
BioImage Archive: Rhoptry biogenesis in Plasmodium sporozoites is uncoupled from mitosis and forms distinct pairs (View on source archive ↗)AFDSI-CELL-596
BioImage Archive: Striated fiber assemblins and associated proteins in Plasmodium falciparum (View on source archive ↗)AFDSI-CELL-597
BioImage Archive: Progressive heterogeneity of enlarged and irregularly shaped apicoplasts in P. falciparum persister blood stages after drug treatment (View on source archive ↗)AFDSI-CELL-598
BioImage Archive: Label-free imaging and classification of live P. falciparum: raw Leica dataset (View on source archive ↗)AFDSI-CELL-599
BioImage Archive: Label-free imaging and classification of live P. falciparum: processed UV dataset (View on source archive ↗)AFDSI-CELL-600
BioImage Archive: A machine learning approach to define antimalarial drug action from heterogeneous cell-based screens (OME-NGFF) (View on source archive ↗)AFDSI-CELL-601
Geographic range (Africa)
8,801 real GBIF-recorded occurrences across Africa — see this species on GBIF ↗.
This reflects real occurrence records submitted to GBIF, not a comprehensive range map — sampling effort varies significantly by country and region, so an absence here doesn't mean the species isn't present.