Leishmania infantum

Also known as: Leishmania (Leishmania) infantum, Leishmania donovani infantum

Indigenous / local names

No local or indigenous names recorded yet.

Status in Africa

Not yet assessed

Occurrence records: Recorded mostly outside Africa. 123 of 1,567 GBIF records (8%) are from Africa (checked 10/9/2026). A hint from GBIF and the genomes on this Hub, not an assessment: GBIF includes zoo and travel records.

Taxonomic classification

cellular organisms; Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina; Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum

View at source ↗

Related species in the DataBank

Species that share this one's nearest groups in NCBI Taxonomy. This is how they're classified, not a phylogeny. See it in the species tree.

Also in Leishmania donovani species complex

Leishmania donovani · 2 genomes, 1 transcriptome, 90 proteins, 143 protein structures, 79 chemical profiles, 3 metabolic profiles, 3 cellular and molecular images

Also in Leishmania

Leishmania aethiopica · 1 genome, 21 proteins, 30 protein structures, 5 chemical profiles, 3 cellular and molecular images
Leishmania aethiopica L147 · 1 genome, 3 cellular and molecular images
Leishmania sp. Ghana 2012 LV757 · 2 genomes, 1 transcriptome, 1 metabolic profile, 12 cellular and molecular images
Leishmania sp. Namibia · 2 genomes, 1 transcriptome, 1 metabolic profile, 13 cellular and molecular images
Leishmania tarentolae · 1 genome, 1 transcriptome, 88 proteins, 153 protein structures, 6 chemical profiles, 3 cellular and molecular images

Also in Trypanosomatidae

Lafontella sp. GMO-01 · 1 genome, 2 proteins, 2 protein structures, 12 cellular and molecular images

Genome browser

The assembly file for Leishmania infantum hasn't finished reaching the Hub yet — check back shortly.

Sequence records

transcriptome (fasta)

mirrored

Origin: hub

0 downloads

First synced: 8/26/2026 · Last updated: 8/26/2026

Source: NCBI OR818042.1 · View at source ↗

Collection: Sri Lanka

Released: 2024-01-29

publiccc0AFDSI-SEQ-625 Benefit-sharing under CBD Decision 16/2 and national frameworks →

Country of origin: LK · PIC: unknown · MAT: unknown

Publicly accessible — no request needed.

genome (fasta)

mirrored

Origin: hub

0 downloads

First synced: 8/26/2026 · Last updated: 8/26/2026

Source: NCBI GCA_037178145.1 · View at source ↗

Collection: Tunisia: Monastir

Sequencing: Oxford Nanopore GridION · GS De Novo Assembler v. 2023 · 4860x coverage

Released: 2024-03-15 · Submitted by: Nano1Health

publiccc0AFDSI-SEQ-221 Benefit-sharing under CBD Decision 16/2 and national frameworks →

Country of origin: TN · PIC: unknown · MAT: unknown

GoaT: Contig assembly · 0.03 Gb · scaffold N50 631,274 · View at source ↗

Publicly accessible — no request needed.

Proteins (74)

protein 2228 — 560 aa

protein 2229 — 365 aa

protein 2230 — 375 aa

protein 2231 — 671 aa

JBP1 — 814 aa

FEN1 — 395 aa

protein 2234 — 895 aa

protein 2235 — 834 aa

protein 2236 — 409 aa

protein 2237 — 412 aa

AlphaFold DB proteome: UP000008153 ↗

Proteomics (external sources)

PRIDE — project-level reference (metadata only; no per-protein identifications are available via PRIDE's public API)

Proteomic Dataset of Non-Specific Interactors in Leishmania infantum (PXD067464) ↗AFDSI-PROJREF-206

Affinity purification-mass spectrometry to identify proteins interacting with Leishmania LINF_180011100 (PXD062031) ↗AFDSI-PROJREF-207

Extracellular vesicles proteomic profile in anti-TNF immunosuppressed mice: insights into protein dysregulation during Leishmania infantum infection (PXD060935) ↗AFDSI-PROJREF-208

Proteomic analysis of Plasma-derived Extracellular Vesicles reveals different biomarkers for monitoring visceral leishmaniasis progression (PXD060604) ↗AFDSI-PROJREF-209

Quantitative proteomics of infected macrophages reveals novel Leishmania virulence factors (PXD058427) ↗AFDSI-PROJREF-211

Mass spectrometry analysis of the Skp1 and Cullin1 interactome in Leishmania infantum (PXD051961) ↗AFDSI-PROJREF-212

Proteomic characterization of extracellular vesicles recovered from peripheral blood from a patient with active leishmaniasis in the context of HIV co-infection (PXD049001) ↗AFDSI-PROJREF-213

T. brucei whole cell proteome changes upon exposure to the experimental phthalimide-based trypanocidal drug PHT-39 (PXD043204) ↗AFDSI-PROJREF-214

DIA-MS serum proteomics in dogs with leishmaniosis (PXD039765) ↗AFDSI-PROJREF-215

Chemical Profiles (external sources)

ChEMBL rows are compounds active against a protein target from this organism — not confirmed as compounds the species itself produces, unlike ANPDB's.

ChEMBL: CHEMBL164580 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 100000.0 nMAFDSI-METABOLOMICS-385

ChEMBL: CHEMBL166314 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 100000.0 nMAFDSI-METABOLOMICS-386

ChEMBL: CHEMBL165097 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 100000.0 nMAFDSI-METABOLOMICS-387

ChEMBL: CHEMBL166092 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 6750.0 nMAFDSI-METABOLOMICS-388

ChEMBL: CHEMBL349670 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 100000.0 nMAFDSI-METABOLOMICS-389

ChEMBL: CHEMBL166069 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 100000.0 nMAFDSI-METABOLOMICS-390

ChEMBL: CHEMBL350978 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 23300.0 nMAFDSI-METABOLOMICS-391

ChEMBL: CHEMBL350506 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 100000.0 nMAFDSI-METABOLOMICS-392

ChEMBL: CHEMBL166182 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 3700.0 nM

Metabolic Profiles (external sources)

KEGG: KEGG genome-based metabolic profile (lif) (View at source ↗) — Genome-based pathway inference (KEGG) — reflects which metabolic pathways this species' annotated genes place it in, not experimentally measured metabolite presenceAFDSI-METABPROF-112

Protein Structures

protein 2248 — v2

pLDDT confidence: unknown

Auto-synced from PDBe 6az1 · View at source ↗

publiccc_byAFDSI-STRUCT-5289-V2

protein 10230 — v2

pLDDT confidence: 73.1

Auto-synced from AlphaFold DB AF-A4HVV6-F1 · View at source ↗

publiccc_byAFDSI-STRUCT-13443-V2

protein 10221 — v2

pLDDT confidence: 84.1

Auto-synced from AlphaFold DB AF-A4I738-F1 · View at source ↗

publiccc_byAFDSI-STRUCT-13429-V2

MPK3 — v2

pLDDT confidence: 89.8

Auto-synced from AlphaFold DB AF-A4HUG1-F1 · View at source ↗

publiccc_byAFDSI-STRUCT-13439-V2

protein 10220 — v2

pLDDT confidence: 90.2

Auto-synced from AlphaFold DB AF-A4I438-F1 · View at source ↗

publiccc_byAFDSI-STRUCT-13427-V2

Cellular & Molecular Imaging (external sources)

BioImage Archive: Micro-CT visualization of a promastigote secretory gel (PSG) and parasite plug in the digestive tract of the sand fly Lutzomyia longipalpis infected with Leishmania mexicana (View on source archive ↗)AFDSI-CELL-471

BioImage Archive: TrypTag: Genome-wide subcellular protein localisation in Trypanosoma brucei. (View on source archive ↗)AFDSI-CELL-472

BioImage Archive: LeishTag: Leishmania protein subcellular localisation through the life cycle (View on source archive ↗)AFDSI-CELL-6906

Geographic range (Africa)

124 real GBIF-recorded occurrences across Africa — see this species on GBIF ↗.

This reflects real occurrence records submitted to GBIF, not a comprehensive range map — sampling effort varies significantly by country and region, so an absence here doesn't mean the species isn't present.

Derived analysis results

A node's own derived bioinformatics-analysis output (e.g. an SSR/microsatellite discovery archive) run against this species' own genome data — see the Derived Analysis page for the full catalog.

GCA_037178145.1

MegaSSR — ssr_discovery

derived from genome record AFDSI-SEQ-221

File: GCA_037178145.1_megassr_results.tar.gz

Tool version: MegaSSR v3.0.0 (UM6P patched)

Native — captured by Northern-MA-UM6P-8787752738 · View at source ↗

cc_by public Country of origin not recorded: see how benefit-sharing works →

AFDSI-ANALYSIS-17172

Obscuromonas oborniki

· 1 genome

Trypanosoma boissoni · 1 genome, 1 protein, 1 protein structure, 5 cellular and molecular images

Trypanosoma congolense

Trypanosoma congolense IL3000 · 1 genome, 5 cellular and molecular images

Trypanosoma equiperdum · 2 genomes, 1 transcriptome, 77 proteins, 140 protein structures, 17 chemical profiles, 5 cellular and molecular images

Trypanosoma grayi · 2 genomes, 1 transcriptome, 22 proteins, 44 protein structures, 5 cellular and molecular images

Wallacemonas sp. TrypX · 1 genome, 12 cellular and molecular images

AFDSI-METABOLOMICS-393

ChEMBL: CHEMBL351276 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 100000.0 nMAFDSI-METABOLOMICS-394

ChEMBL: CHEMBL242165 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition 70.0 %AFDSI-METABOLOMICS-395

ChEMBL: CHEMBL242163 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition %AFDSI-METABOLOMICS-396

ChEMBL: CHEMBL4097340 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 75000.0 nMAFDSI-METABOLOMICS-397

ChEMBL: CHEMBL4070159 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 14400.0 nMAFDSI-METABOLOMICS-398

ChEMBL: CHEMBL4105040 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 9900.0 nMAFDSI-METABOLOMICS-399

ChEMBL: CHEMBL4080816 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 20800.0 nMAFDSI-METABOLOMICS-400

ChEMBL: CHEMBL4076896 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 13500.0 nMAFDSI-METABOLOMICS-401

ChEMBL: CHEMBL4129161 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition %AFDSI-METABOLOMICS-402

ChEMBL: CHEMBL4290914 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition %AFDSI-METABOLOMICS-403

ChEMBL: CHEMBL4281347 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition %AFDSI-METABOLOMICS-404

ChEMBL: CHEMBL4276822 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition %AFDSI-METABOLOMICS-405

ChEMBL: CHEMBL4128885 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition %AFDSI-METABOLOMICS-406

ChEMBL: CHEMBL3629567 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Kd 8.4 nMAFDSI-METABOLOMICS-407

ChEMBL: CHEMBL1236677 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Kd 2.0 nMAFDSI-METABOLOMICS-408

ChEMBL: CHEMBL3503055 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Percent Effect -2.778 %AFDSI-METABOLOMICS-409

ChEMBL: CHEMBL3442215 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Percent Effect -1.389 %AFDSI-METABOLOMICS-410

ChEMBL: CHEMBL3442218 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Percent Effect -4.167 %AFDSI-METABOLOMICS-411

ChEMBL: CHEMBL3442273 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Percent Effect 8.333 %AFDSI-METABOLOMICS-412

ChEMBL: CHEMBL3499903 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Percent Effect 1.389 %AFDSI-METABOLOMICS-413

ChEMBL: CHEMBL3503095 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Percent Effect 9.722 %AFDSI-METABOLOMICS-414

ChEMBL: CHEMBL3503077 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Percent Effect -1.389 %AFDSI-METABOLOMICS-415

ChEMBL: CHEMBL3503057 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Percent Effect 11.11 %AFDSI-METABOLOMICS-416

ChEMBL: CHEMBL3499880 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Percent Effect 16.67 %AFDSI-METABOLOMICS-417

ChEMBL: CHEMBL3504617 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Percent Effect 5.556 %AFDSI-METABOLOMICS-418

ChEMBL: SURFACTIN (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 35200.0 nMAFDSI-METABOLOMICS-615

ChEMBL: BNIPDANON (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 5700.0 nMAFDSI-METABOLOMICS-616

ChEMBL: BNIPDAOCT (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 9200.0 nMAFDSI-METABOLOMICS-617

ChEMBL: SIRTINOL (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 193800.0 nMAFDSI-METABOLOMICS-618

ChEMBL: NIACINAMIDE (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 39400.0 nMAFDSI-METABOLOMICS-619

ChEMBL: CHEMBL4216559 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 5700.0 nMAFDSI-METABOLOMICS-620

ChEMBL: SURAMIN (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 7000.0 nMAFDSI-METABOLOMICS-621

ChEMBL: CHEMBL4211052 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 5700.0 nMAFDSI-METABOLOMICS-622