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Leishmania donovani

taxon 5661

Also known as: Leishmania (Leishmania) donovani

Indigenous / local names

No local or indigenous names recorded yet.

Genome browser

Sequence records

genome (fasta)

mirrored

Origin: hub

43 downloads

First synced: 9/1/2026 · Last updated: 9/1/2026

Source: NCBI GCA_003730175.1 · View at source ↗

Download annotation (GFF3) · Download CDS (FASTA) · Download proteins (FASTA)

Sequencing: PacBio; Illumina · canu v. 1.2 · 456x coverage

publiccc0AFDSI-SEQ-801

GoaT: Chromosome assembly · 0.03 Gb · scaffold N50 1,015,993 · 36 chromosomes · View at source ↗

Publicly accessible — no request needed.

Proteins (1)

NT1.1 491 aa

genome (fasta)

mirrored

Origin: hub

43 downloads

First synced: 9/1/2026 · Last updated: 9/1/2026

Source: NCBI GCA_003730215.1 · View at source ↗

Download annotation (GFF3) · Download CDS (FASTA) · Download proteins (FASTA)

Sequencing: PacBio; Illumina · Canu v. 1.2 · 541x coverage

publiccc0AFDSI-SEQ-802

GoaT: Chromosome assembly · 0.03 Gb · scaffold N50 1,015,993 · 36 chromosomes · View at source ↗

Publicly accessible — no request needed.

transcriptome (fasta)

mirrored

Origin: hub

0 downloads

First synced: 9/2/2026 · Last updated: 9/2/2026

Source: NCBI OR058908.1 · View at source ↗

Released: 2024-12-28

publiccc0AFDSI-SEQ-971

Publicly accessible — no request needed.

AlphaFold DB proteome: UP000274082

Proteomics (external sources)

PRIDE — project-level reference (metadata only; no per-protein identifications are available via PRIDE's public API)

Analysis of proteins immunoprecipitated with anti-FLAG antibodies from Leishmania donovani promastigotes expressing Cdc45-FLAG or carrying empty vector (PXD064001) ↗AFDSI-PROJREF-392

Exploring the mode of action of a novel antileishmanial compound using thermal proteome profiling and other OMICs tools (PXD063779) ↗AFDSI-PROJREF-393

Leishmania regulates host YY1: comparative proteomic analysis identifies infection modulated YY1 dependent proteinsLeishmania regulates host YY1: comparative proteomic analysis identifies infection modulated YY1 dependent proteins (PXD059968) ↗AFDSI-PROJREF-394

Proteomics analysis of lysine methylated proteins from Leishmania donovani strain 1S: wild type and set mutants (PXD057511) ↗AFDSI-PROJREF-395

Proteomics analysis of lysine methylated proteins from Leishmania donovani strain 1S: wild type and set mutants (PXD057513) ↗AFDSI-PROJREF-396

Proteomics analysis of lysine methylated proteins from Leishmania donovani strain 1S: wild type and set mutants (PXD057514) ↗AFDSI-PROJREF-397

Proteomics analysis of lysine methylated proteins from Leishmania donovani strain 1S: wild type and set mutants (PXD056970) ↗AFDSI-PROJREF-398

Sterol 14-alpha demethylase (CYP51) activity in Leishmania donovani is likely dependent upon cytochrome P450 reductase 1 (PXD052472) ↗AFDSI-PROJREF-399

Experimental proteome of Leishmania donovani (HU3 strain) promastigotes (PXD051920) ↗AFDSI-PROJREF-400

An oligosaccharyltransferase from Leishmania donovani increases the N-glycan occupancy on plant-produced IgG1 (PXD043623) ↗AFDSI-PROJREF-401

Chemical Profiles (external sources)

ChEMBL rows are compounds active against a protein target from this organism — not confirmed as compounds the species itself produces, unlike ANPDB's.

ChEMBL: CHEMBL181441 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 30000.0 nMAFDSI-METABOLOMICS-1041

ChEMBL: CHEMBL181587 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 30000.0 nMAFDSI-METABOLOMICS-1043

ChEMBL: CHEMBL181441 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 30000.0 nMAFDSI-METABOLOMICS-1040

ChEMBL: CHEMBL181587 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 30000.0 nMAFDSI-METABOLOMICS-1042

ChEMBL: CHEMBL365485 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 300000.0 nMAFDSI-METABOLOMICS-1044

ChEMBL: CHEMBL182868 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 10000.0 nMAFDSI-METABOLOMICS-1046

ChEMBL: CHEMBL182906 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 10000.0 nMAFDSI-METABOLOMICS-1048

ChEMBL: CIRRHOPETALANTHRIN (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 30000.0 nMAFDSI-METABOLOMICS-1051

ChEMBL: CIRRHOPETALANTHIN (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 30000.0 nMAFDSI-METABOLOMICS-1052

ChEMBL: CHEMBL88370 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition 80.0 %AFDSI-METABOLOMICS-1077

ChEMBL: CHEMBL365485 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 300000.0 nMAFDSI-METABOLOMICS-1045

ChEMBL: CHEMBL182868 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 10000.0 nMAFDSI-METABOLOMICS-1047

ChEMBL: CHEMBL182906 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 10000.0 nMAFDSI-METABOLOMICS-1049

ChEMBL: CIRRHOPETALANTHRIN (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 30000.0 nMAFDSI-METABOLOMICS-1050

ChEMBL: CIRRHOPETALANTHIN (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 30000.0 nMAFDSI-METABOLOMICS-1054

ChEMBL: VINBLASTINE (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 1000.0 nMAFDSI-METABOLOMICS-1057

ChEMBL: CHEMBL313163 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition 36.0 %AFDSI-METABOLOMICS-1058

ChEMBL: CHEMBL315544 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition 30.0 %AFDSI-METABOLOMICS-1060

ChEMBL: CHEMBL89104 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition 0.0 %AFDSI-METABOLOMICS-1062

ChEMBL: CHEMBL314694 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition 73.0 %AFDSI-METABOLOMICS-1064

ChEMBL: CHEMBL2079699 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition 86.0 %AFDSI-METABOLOMICS-1066

ChEMBL: CHEMBL328924 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition 63.0 %AFDSI-METABOLOMICS-1068

ChEMBL: CHEMBL88891 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition 0.0 %AFDSI-METABOLOMICS-1070

ChEMBL: CHEMBL91676 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition 62.0 %AFDSI-METABOLOMICS-1072

ChEMBL: CHEMBL327809 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition 78.0 %AFDSI-METABOLOMICS-1074

ChEMBL: CHEMBL185178 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 30000.0 nMAFDSI-METABOLOMICS-1053

ChEMBL: VINBLASTINE (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 1000.0 nMAFDSI-METABOLOMICS-1055

ChEMBL: COMBRETASTATIN A4 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 1900.0 nMAFDSI-METABOLOMICS-1056

ChEMBL: CHEMBL313163 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition 36.0 %AFDSI-METABOLOMICS-1059

ChEMBL: CHEMBL315544 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition 30.0 %AFDSI-METABOLOMICS-1061

ChEMBL: CHEMBL89104 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition 0.0 %AFDSI-METABOLOMICS-1063

ChEMBL: CHEMBL314694 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition 73.0 %AFDSI-METABOLOMICS-1065

ChEMBL: CHEMBL2079699 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition 86.0 %AFDSI-METABOLOMICS-1067

ChEMBL: CHEMBL328924 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition 63.0 %AFDSI-METABOLOMICS-1069

ChEMBL: CHEMBL88891 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition 0.0 %AFDSI-METABOLOMICS-1071

ChEMBL: CHEMBL91676 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition 62.0 %AFDSI-METABOLOMICS-1073

ChEMBL: CHEMBL327809 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition 78.0 %AFDSI-METABOLOMICS-1075

ChEMBL: CHEMBL88370 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition 80.0 %AFDSI-METABOLOMICS-1076

ChEMBL: CHEMBL204200 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 23500.0 nMAFDSI-METABOLOMICS-1079

ChEMBL: LEUPEPTIN (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 10.0 nMAFDSI-METABOLOMICS-1081

ChEMBL: CHEMBL381970 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 43000.0 nMAFDSI-METABOLOMICS-1083

ChEMBL: CHEMBL204200 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 23500.0 nMAFDSI-METABOLOMICS-1078

ChEMBL: LEUPEPTIN (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 10.0 nMAFDSI-METABOLOMICS-1080

ChEMBL: CHEMBL381970 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 43000.0 nMAFDSI-METABOLOMICS-1082

ChEMBL: CHEMBL426667 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 31400.0 nMAFDSI-METABOLOMICS-1084

ChEMBL: CHEMBL204036 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 24900.0 nMAFDSI-METABOLOMICS-1086

ChEMBL: CHEMBL224801 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 72000.0 nMAFDSI-METABOLOMICS-1088

ChEMBL: CHEMBL224915 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 129500.0 nMAFDSI-METABOLOMICS-1090

ChEMBL: CHEMBL426564 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 62600.0 nMAFDSI-METABOLOMICS-1092

ChEMBL: CHEMBL222325 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 112900.0 nMAFDSI-METABOLOMICS-1094

ChEMBL: CHEMBL222870 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 65300.0 nMAFDSI-METABOLOMICS-1097

ChEMBL: CHEMBL298547 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 19940.0 nMAFDSI-METABOLOMICS-1098

ChEMBL: (OCTYLAMINO)METHYLENEDIPHOSPHONIC ACID (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 1060.0 nMAFDSI-METABOLOMICS-1100

ChEMBL: ZOLEDRONIC ACID (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 110.0 nMAFDSI-METABOLOMICS-1102

ChEMBL: CHEMBL55359 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 100000.0 nMAFDSI-METABOLOMICS-1104

ChEMBL: CHEMBL54537 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 500.0 nMAFDSI-METABOLOMICS-1106

ChEMBL: CHEMBL426667 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 31400.0 nMAFDSI-METABOLOMICS-1085

ChEMBL: CHEMBL204036 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 24900.0 nMAFDSI-METABOLOMICS-1087

ChEMBL: CHEMBL224801 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 72000.0 nMAFDSI-METABOLOMICS-1089

ChEMBL: CHEMBL224915 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 129500.0 nMAFDSI-METABOLOMICS-1091

ChEMBL: CHEMBL426564 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 62600.0 nMAFDSI-METABOLOMICS-1093

ChEMBL: CHEMBL222325 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 112900.0 nMAFDSI-METABOLOMICS-1095

ChEMBL: CHEMBL222870 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 65300.0 nMAFDSI-METABOLOMICS-1096

ChEMBL: CHEMBL298547 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 19940.0 nMAFDSI-METABOLOMICS-1099

ChEMBL: (OCTYLAMINO)METHYLENEDIPHOSPHONIC ACID (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 1060.0 nMAFDSI-METABOLOMICS-1101

ChEMBL: ZOLEDRONIC ACID (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 110.0 nMAFDSI-METABOLOMICS-1103

ChEMBL: CHEMBL55359 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 100000.0 nMAFDSI-METABOLOMICS-1105

ChEMBL: CHEMBL54537 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 500.0 nMAFDSI-METABOLOMICS-1107

ChEMBL: CHEMBL55371 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 100000.0 nMAFDSI-METABOLOMICS-1109

ChEMBL: CHEMBL294192 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 170.0 nMAFDSI-METABOLOMICS-1111

ChEMBL: CHEMBL299491 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 100000.0 nMAFDSI-METABOLOMICS-1113

ChEMBL: CHEMBL55371 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 100000.0 nMAFDSI-METABOLOMICS-1108

ChEMBL: CHEMBL294192 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 170.0 nMAFDSI-METABOLOMICS-1110

ChEMBL: CHEMBL299491 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 100000.0 nMAFDSI-METABOLOMICS-1112

ChEMBL: CHEMBL301244 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 310.0 nMAFDSI-METABOLOMICS-1114

ChEMBL: CHEMBL55988 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 480.0 nMAFDSI-METABOLOMICS-1116

ChEMBL: CHEMBL281021 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; Inhibition 76.0 %AFDSI-METABOLOMICS-1118

ChEMBL: CHEMBL301244 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 310.0 nMAFDSI-METABOLOMICS-1115

ChEMBL: CHEMBL55988 (View at source ↗) — Target organism (ChEMBL) — not confirmed as a compound this species produces; IC50 480.0 nMAFDSI-METABOLOMICS-1117

Metabolic Profiles (external sources)

MetaboLights: Four layer multi-omics reveals molecular responses to aneuploidy in Leishmania (View at source ↗)AFDSI-METABPROF-145

MetaboLights: Integrated genomic and metabolomic profiling of ISC1, an emerging Leishmania donovani population in the Indian subcontinent (View at source ↗)AFDSI-METABPROF-144

KEGG: KEGG genome-based metabolic profile (ldo) (View at source ↗) — Genome-based pathway inference (KEGG) — reflects which metabolic pathways this species' annotated genes place it in, not experimentally measured metabolite presenceAFDSI-METABPROF-156

Cellular & Molecular Imaging (external sources)

BioImage Archive: Micro-CT visualization of a promastigote secretory gel (PSG) and parasite plug in the digestive tract of the sand fly Lutzomyia longipalpis infected with Leishmania mexicana (View on source archive ↗)AFDSI-CELL-928

BioImage Archive: TrypTag: Genome-wide subcellular protein localisation in Trypanosoma brucei. (View on source archive ↗)AFDSI-CELL-929

Geographic range (Africa)

922 real GBIF-recorded occurrences across Africa — see this species on GBIF ↗.

This reflects real occurrence records submitted to GBIF, not a comprehensive range map — sampling effort varies significantly by country and region, so an absence here doesn't mean the species isn't present.